When mixing regular and NPH insulin, what should the nurse do first?

When mixing regular and NPH insulin, the first step is to inject air into the NPH insulin vial. This procedure ensures that the NPH insulin is properly prepared for drawing up the required dose. By injecting air into the NPH vial first, the nurse prevents the risk of creating a vacuum that can occur when drawing out the NPH insulin, thereby making the process easier and more accurate.

Injecting air into the vial before drawing the insulin helps in maintaining the correct pressure within the vial, allowing the insulin to be drawn up smoothly. It is standard practice to add air to the NPH vial first, as the longer-acting NPH insulin must be handled with care. When mixing insulins, this technique is crucial for ensuring that each type is properly administered without contamination or incorrect dosage.

The technique of injecting air into the vials is fundamental to proper insulin mixing and administration, helping to maintain safety and efficacy in the treatment of diabetes.