Which symptom is least likely to indicate an opioid overdose?

An increased respiratory rate is generally not a symptom associated with opioid overdose; in fact, opioids typically lead to respiratory depression, which results in a decreased respiratory rate. Opioids act on the central nervous system to depress bodily functions, and one of the most serious effects is the reduction in the drive to breathe. This is critical to note when assessing a patient for possible opioid overdose.

In contrast, a decreased level of consciousness, decreased blood pressure, and pinpoint pupils are classic signs of opioid intoxication or overdose. The combination of these symptoms indicates significant central nervous system depression that can lead to life-threatening complications. Understanding these distinctions is essential for healthcare professionals in identifying and responding to opioid overdose situations effectively.